Scientists filmed bacteria evolve resistance to 1,000x-strength antibiotics in 11 days

Harvard's Kishony lab built a two-foot-wide petri dish with bands of steadily increasing antibiotic concentration, then released E. coli at one end and filmed it with a time-lapse camera. Within 11 days, descendants of the original bacteria had fought through bands 1,000 times the initial lethal dose, visibly branching and pausing wherever a new resistance mutation had to arise. The 2016 video turned an abstract idea, evolution under selection pressure, into something you can watch happen.

— Michael Baym, Roy Kishony et al., Spatiotemporal microbial evolution on antibiotic landscapes — Science, vol. 353, 2016

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