A silent patient nicknamed 'Tan' proved language lives in one spot in the brain

In 1861, surgeon Paul Broca examined a patient who understood language but could only say the syllable 'tan.' An autopsy after his death found damage concentrated in one region of the left frontal lobe -- the first solid evidence that specific mental functions map onto specific brain locations, not the brain as an undifferentiated whole.

— Paul Broca, Remarks on the Seat of the Faculty of Articulated Language — Bulletin de la Société Anatomique, 1861

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